Custom synthesis Available Apoptosis Library Chemical Structure: MIK665 CAS No.: 1799631-75-6 聽 MIK665(MIK 665, S 64315, S64315) Catalog No.: URK-V595聽聽Only Used For Lab. MIK665 (S-64315, MIK-665) is a novel potent, selective Mcl-1 inhibitor (IC50=1.8 nM) with potential pro-apoptotic and antineoplastic activities. 聽 Biological Activity MIK665 (S-64315, MIK-665) is a novel potent, selective Mcl-1 inhibitor (IC50=1.8 nM) with potential pro-apoptotic and antineoplastic activities. MIK665 (S-64315) binds to and inhibits the activity of Mcl-1, which promotes apoptosis of cells overexpressing Mcl-1. Mcl-1, an anti-apoptotic protein belonging to the Bcl-2 family of proteins, is upregulated in cancer cells and promotes tumor cell survival. 聽 Physicochemical Properties M.Wt875.413 FormulaC47H44ClFN6O6S CAS No.1799631-75-6 StorageSolide Powder -20 掳C 3years; 4掳C 2yearsIn Solvent -80掳C 6 Months -20掳C 1 Months Solubility10 mM in DMSO Chemical Name(R)-2-((5-(3-chloro-2-methyl-4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl)oxy)-3-(2-((2-(2-methoxyphenyl)pyrimidin-4-yl)methoxy)phenyl)propanoic acid 聽 References 1. Cassier PA, et al. Br J Cancer. 2017 Oct 10;117(8):1089-1098. URK-V595_COA URK-V595_SDS URK-V595_TDS 聽 Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use 聽Custom synthesis Available Apoptosis Library website:http://www.ureiko-chem.com/inhibitors-agonists/apoptosis-library/
Rechercher
Catégories
- Art
- Causes
- Crafts
- Dance
- Drinks
- Film
- Fitness
- Food
- Jeux
- Gardening
- Health
- Home
- Literature
- Music
- Networking
- Other
- Party
- Religion
- Shopping
- Sports
- Theater
- Wellness
Read More
Don’t Delay When It Comes To Using Tech Blog
Travel bloggers provide an amazing quantity of knowledge, inspiration and tips. They will...
How to style your linen shorts for a fashion-forward look
Introduction
When it comes to summer fashion, linen shorts have always been a classic choice for...
Instructions on how to bet on penalty cards accurately from experts
Betting on penalty cards, also known as booking points or card betting, involves...
How Midea Air Fryers Revolutionize Cooking in the Modern Kitchen
Regardless of the wind, the sun rises and we can see midea air fryer.
When it comes to modern...
Diablo 4 Power Leveling Guide: How to Level Efficiently in Diablo 4
It will be a real challenge for most players to reach level 100 in D4, taking up to 150 hours to...