Enemy Resistances and Path of Exile 2 Currency Penetration:
Enemy resistances reduce damage according to their resist values, while penetration mechanics reduce these resistances temporarily to increase damage dealt.

Damage Taken Modifiers:
Additional modifiers on the enemy, such as increased damage taken from hits or spells, are factored in here.

Damage Avoidance:
After damage calculation, avoidance mechanics like dodge, block, or evasion chance determine if damage is mitigated or negated.

Defense Calculation Highlights
Evasion and Dodge:
Determine if an enemy avoids incoming hits entirely.

Block:
Chance to reduce or negate damage.

Armour and Energy Shield:
Reduce or absorb incoming damage before it affects life.

Life Regeneration and Recovery:
Heal damage over time.

Why This Matters
Build Optimization: Knowing when each modifier applies allows you to prioritize stats and gear that maximize damage or survivability.

Strategic Planning: Some effects interact differently depending on their place in the order, impacting how you approach combat.

Mechanics Mastery: Certain skills or items can exploit specific parts of the order for greater effect.

By understanding Path of Exile 2’s order of operations, players can design more effective and efficient builds that maximize their damage output and path of exile 2 trade defense, improving overall gameplay performance.